Lysosomal Storage Disorders Shed Light on Lysosomal Dysfunction in Parkinson’s Disease
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منابع مشابه
Lysosomal storage disorders: The cellular impact of lysosomal dysfunction
Lysosomal storage diseases (LSDs) are a family of disorders that result from inherited gene mutations that perturb lysosomal homeostasis. LSDs mainly stem from deficiencies in lysosomal enzymes, but also in some non-enzymatic lysosomal proteins, which lead to abnormal storage of macromolecular substrates. Valuable insights into lysosome functions have emerged from research into these diseases. ...
متن کاملMitochondrial Dysfunction in Lysosomal Storage Disorders
Lysosomal storage diseases (LSDs) describe a heterogeneous group of rare inherited metabolic disorders that result from the absence or loss of function of lysosomal hydrolases or transporters, resulting in the progressive accumulation of undigested material in lysosomes. The accumulation of substances affects the function of lysosomes and other organelles, resulting in secondary alterations suc...
متن کاملThe cell biology of disease Lysosomal storage disorders : The cellular impact of lysosomal dysfunction
Correspondence to Frances M. Platt: [email protected]; Barry Boland: [email protected]; or Aarnoud C. van der Spoel: [email protected] Abbreviations used in this paper: CNS, central nervous system; LSD, lysosomal storage disease; NPC, Niemann-Pick type C. Lysosomal storage disorders: A brief overview Inborn errors of metabolism are a common cause of inherited disease (Burton, 1998), of...
متن کاملlysosomal storage disease (lsds)
how to cite this article: ghofrani m. lysosomal storage disease (lsds). iran j child neurol. 2015 autumn;9:4(suppl.1): 1. pls see pdf.
متن کاملlysosomal storage disease
how to cite this article: ghofrani m. lysosomal storage disease. iran j child neurol autumn 2012; 6:4 (suppl. 1):1-2. for reading more pls see pdf
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ژورنال
عنوان ژورنال: International Journal of Molecular Sciences
سال: 2020
ISSN: 1422-0067
DOI: 10.3390/ijms21144966